Jenna S. Moore

Document Type

Honors Project

First Advisor

Dr. Robyn Puffenbarger

Degree Award Date

Spring 2005


Molecular Regulation, CB2 Receptor, cannabinoid receptor, ligand modulation


Biology | Cell and Developmental Biology | Cell Biology | Laboratory and Basic Science Research


The cannabinoid receptor system plays an integral role in the transmittance of signals between cells of the immune system through ligand modulation. The ligation of these receptors has the ability to activate and suppress a wide variety of immune functions. One receptor involved in this communication process is the CB2 receptor, which is most commonly found on T-cells, B-cells and macrophages. In order to better understand the effects of CB2 receptors, the production and regulation of the CB2 receptors themselves must be understood. The purpose of this research is to isolate the start of transcription for the CB2 mRNA.