Angela Spinelli

Document Type

Honors Project

First Advisor

Dr. Moshe Khurgel

Degree Award Date

Spring 2011


Differential Gene Expression, Mexican Axolotl, Spinal Cord Regeneration, Tail Regeneration


Biology | Cell Biology | Zoology


The Mexican axolotl, also known as Ambystoma mexicanum, is able to regenerate tails, limbs and other body parts after amputation. Spinal cord regeneration is of particular interest to humans, because of the inability of the human body to regenerate an injured spinal cord. This project examined protein expression in the regenerating tails of developing Mexican axolotls. In particular, this project intended to look at the expression of cellular nucleic acid binding protein (CNBP), with respect to different stages of tail regeneration. Although no concrete data resulted from this project, useful techniques were learned and developed throughout the duration of the project.